Mourinho, 60, had been at the helm of the Serie A club since the summer of 2021 and guided them to the Europa Conference League title in 2022 and the Europa League final the following season.
However, Roma have struggled domestically and currently sit ninth in the Italian top-flight — Sunday’s 3-1 loss at Milan was their third defeat in five league games and has proved to be Mourinho’s final game as boss.